[A21-55] Olaparib (ovarian cancer; first-line maintenance in combination with bevacizumab) - Addendum to Commission A20-111

Last updated 04.06.2021

Project no.:

Commission awarded on 28.04.2021 by the Federal Joint Committee (G-BA).

Report type:

Commission completed

Drug Assessment

Application field:


Maintenance therapy of adult patients with advanced (FIGO stages III and IV) high-grade epithelial ovarian cancer who are in response (complete or partial) following completion of first-line platinum-based chemotherapy in combination with bevacizumab and whose tumour is associated with HRD-positive status

Result of dossier assessment:

Patients without detectable tumour after primary surgery and patients without detectable tumour/with complete response following chemotherapy: indication of considerable added benefit.

Patients without detectable tumour after interval surgery and patients with partial response: indication of lesser benefit.


If the need for additional work on a project commissioned by the G-BA arises during consultations, then IQWiG presents a report in the form of an "addendum". The G-BA subsequently decides on the extent of the added benefit, thus completing the early benefit assessment.

Federal Joint Committee (G-BA)

2021.06.04 A G-BA decision was published.

G-BA documents on this decision


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