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Early benefit assessment - the whole range

IQWiG assessed a total of 24 manufacturer dossiers on time for the deadlines of 1 March and 15 March. As examples, the indications and results reflect the complexity of the AMNOG procedu...


Nusinersen in SMA: indication of major added benefit in children with early-onset disease

Treatment delays permanent ventilation of the children and prolongs life. In addition, the children develop more motor skills.


Clinical relevance of patient-reported outcomes: new threshold proven feasible in practice

Current examples prove the feasibility of the 15 percent threshold newly defined by IQWiG for the acceptance of responder analyses in ear...


Ibrutinib with rituximab in previously untreated CLL: indication of added benefit over FCR

The new drug combination prolongs overall survival in patients in good general health. No study data are available for other patient groups...

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Easily understandable information for the general public

InformedHealth.org is the English-language version of the German website Gesundheitsinformation.de. By publishing this bilingual website, IQWiG fulfils part of its legal mandate to inform the general public about health issues. By offering a wide range of different topics, the website addresses both patients and (healthy) consumers.


Sinusitis is an inflammation of the membranes lining the paranasal sinuses (air-filled spaces around the nose) and the nose itself. It is also known as "rhinosinusitis." "Rhino-" means nose, and "sinus" means a space in the body.


Eczema is a common, chronic, non-infectious skin condition. The main symptom of this inflammatory disease is a very itchy rash. It often affects children. In many cases eczema gets better as the years go by, and it may go away for a while or disappear altogether.