[A20-114] Nusinersen (spinal muscular atrophy) - Benefit assessment according to §35a Social Code Book V

Last updated 20.05.2021

Project no.:

Commission awarded on 02.12.2020 by the Federal Joint Committee (G-BA).

Report type:
Dossier assessment

Commission completed

Drug Assessment

Application field:
Muscles, bones and joints


Patients with 5q spinal muscular atrophy (SMA)

Result of dossier assessment:

Early onset of disease (infantile form, type 1): indication of major added benefit. Later onset of disease (type 2, type 3 and type 4): added benefit not proven. Pre-symptomatic patients: hint of non-quantifiable added benefit.


After completion of the assessment by IQWiG the Federal Joint Committee (G-BA) conducts a commenting procedure. This may provide supplementary information and as a result lead to a modified benefit assessment. Further information and the decision on the early benefit assessment can be found on the relevant page of the G-BA website.

Federal Joint Committee (G-BA)

2021.05.20 A G-BA decision was published.

G-BA documents on this decision


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