[A25-158] Nirmatrelvir/ritonavir (COVID-19, without supplemental oxygen, increased risk of progressing to severe COVID-19, >= 6 years to < 18 years, >= 20 kg) – Benefit assessment according to §35a Social Code Book V

Last updated 16.03.2026

Project no.:
A25-158

Commission:
Commission awarded on 16.12.2025 by the Federal Joint Committee (G-BA).

Report type:
Dossier assessment

Status:
Commission completed

Department/Division:
Drug Assessment

Topic:
Immune system and infections

Indication:

Children and adolescents aged 6 to ≤ 17 years with COVID-19 who do not require supplemental oxygen and who are at increased risk of progressing to severe COVID-19

Result of dossier assessment:
  • Patients weighing between 20 and 40 kg: added benefit not proven
  • Patients weighing at least 40 kg: added benefit not proven
Note:

After completion of the assessment by IQWiG the Federal Joint Committee (G-BA) conducts a commenting procedure. This may provide supplementary information and as a result lead to a modified benefit assessment. Further information and the decision on the early benefit assessment can be found on the relevant page of the G-BA website.

DOI:

https://doi.org/10.60584/A25-158

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