[A19-57] Olaparib (breast cancer) - Benefit assessment according to §35a Social Code Book V

Last updated 15.10.2019

Project no.:
A19-57

Commission:
Commission awarded on 11.07.2019 by the Federal Joint Committee (G-BA).

Report type:
Dossier assessment

Status:
Commission completed

Department/Division:
Drug Assessment

Topic:
Cancer

Indication:

Monotherapy of adult patients with germline BRCA1/2 mutations, who have HER2-negative locally advanced or metastatic breast cancer

Result of dossier assessment:

Without prior chemotherapy for metastatic breast cancer: indication of considerable added benefit; with prior chemotherapy for metastatic breast cancer: hint of considerable added benefit

Note:

After completion of the assessment by IQWiG the Federal Joint Committee (G-BA) conducts a commenting procedure. This may provide supplementary information and as a result lead to a modified benefit assessment. Further information and the decision on the early benefit assessment can be found on the relevant page of the G-BA website.

Project no. Title Status
A19-56 Olaparib (ovarian cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
A18-36 Olaparib (ovarian, fallopian tube, peritoneal cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
A19-97 Olaparib (breast cancer) - Addendum to Commission A19-57 Commission completed
G15-05 Olaparib - Assessment according to §35a (para. 1., sentence 10) Social Code Book V (dossier assessment) Commission completed
A24-88 Olaparib (maintenance in combination with durvalumab; endometrial cancer) – Benefit assessment according to §35a Social Code Book V Commission completed
A22-117 Olaparib (ovarian cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
A23-03 Olaparib (prostate cancer) - Benefit assessment according to § 35a SGB V Commission completed
A20-115 Olaparib (adenocarcinoma of the pancreas) - Benefit assessment according to §35a Social Code Book V Commission completed
A20-106 Olaparib (prostate cancer) - Benefit assessment according to §35a Social Code Book V Commission completed
A20-111 Olaparib (ovarian cancer; first-line maintenance in combination with bevacizumab) - Benefit assessment according to §35a Social Code Book V Commission completed
A23-32 Olaparib (ovarian cancer) – Benefit assessment according to §35a Social Code Book V Commission completed
A22-89 Olaparib (breast cancer, adjuvant) – Benefit assessment according to §35a Social Code Book V Commission completed

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