[A25-139] Momelotinib (myelofibrosis) – Benefit assessment according to §35a Social Code Book V

Last updated 02.02.2026

Project no.:
A25-139

Commission:
Commission awarded on 04.11.2025 by the Federal Joint Committee (G-BA).

Report type:
Dossier assessment

Status:
Commission completed

Department/Division:
Drug Assessment

Topic:
Cancer

Indication:

The treatment of disease-related splenomegaly or symptoms in adults with moderate to severe anaemia who have primary myelofibrosis, post polycythaemia vera myelofibrosis or post essential thrombocythaemia myelofibrosis

Result of dossier assessment:
  • Patients who are JAK inhibitor naïve: added benefit not proven
  • Patients who have been treated with ruxolitinib: added benefit not proven
Note:

After completion of the assessment by IQWiG the Federal Joint Committee (G-BA) conducts a commenting procedure. This may provide supplementary information and as a result lead to a modified benefit assessment. Further information and the decision on the early benefit assessment can be found on the relevant page of the G-BA website.

DOI:

https://doi.org/10.60584/A25-139

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