[A20-08] Upadacitinib (rheumatoid arthritis) - Benefit assessment according to §35a Social Code Book V
Last updated 16.07.2020
Project no.:
A20-08
Commission:
Commission awarded on 16.01.2020 by the Federal Joint Committee (G-BA).
Report type:
Dossier assessment
Status:
Commission completed
Department/Division:
Drug Assessment
Application field:
Muscles, bones and joints
Adults with moderate to severe active rheumatoid arthritis who have responded inadequately to, or who are intolerant to DMARDs
First treatment with bDMARDs or tsDMARDs indicated: for combination with MTX indication of considerable added benefit. Patients with high disease activity who have responded inadequately to, or who are intolerant to one or more bDMARDs and/or tsDMARDs: for combination with MTX indication of minor added benefit. Monotherapy and other patient groups: added benefit not proven.
The current version 1.1 of the dossier assessment replaces version 1.0 published on 2020-05-04.
After completion of the assessment by IQWiG the Federal Joint Committee (G-BA) conducts a commenting procedure. This may provide supplementary information and as a result lead to a modified benefit assessment. Further information and the decision on the early benefit assessment can be found on the relevant page of the G-BA website.
| Project no. | Title | Status |
|---|---|---|
| A23-38 | Upadacitinib (Crohn disease) - Benefit assessment according to §35a Social Code Book V | Commission completed |
| A21-116 | Upadacitinib (atopic dermatitis) - Benefit assessment according to §35a Social Code Book V | Commission completed |
| A22-91 | Upadacitinib (ulcerative colitis) - Benefit assessment according to §35a Social Code Book V | Commission completed |
| A21-16 | Upadacitinib (ankylosing spondylitis) - Benefit assessment according to §35a Social Code Book V | Commission completed |
| A21-15 | Upadacitinib (psoriatic arthritis) - Benefit assessment according to §35a Social Code Book V | Commission completed |
| A22-92 | Upadacitinib (axial spondyloarthritis) - Benefit assessment according to §35a Social Code Book V | Commission completed |