[A26-40] Asciminib (CML, first- and second-line treatment) – Addendum to Project A25-150

Last updated 21.05.2026

Project no.:
A26-40

Commission:
Commission awarded on 08.04.2026 by the Federal Joint Committee (G-BA).

Report type:
Addendum

Status:
Commission completed

Department/Division:
Drug Assessment

Topic:
Cancer

Indication:

Adult patients with Philadelphia chromosome-positive chronic myeloid leukaemia in chronic phase (Ph+ CML-CP)

Result of dossier assessment:
  • Patients undergoing first-line treatment: after addendum now: indication of a minor added benefit
  • Patients who have previously been treated with a tyrosine kinase inhibitor (TKI); second-line treatment: unchanged after addendum: added benefit not proven
Note:

If the need for additional work on a project commissioned by the G-BA arises during consultations, then IQWiG presents a report in the form of an "addendum". The G-BA subsequently decides on the extent of the added benefit, thus completing the early benefit assessment.

DOI:

https://doi.org/10.60584/A26-40

Federal Joint Committee (G-BA)

21-05-2026 A G-BA decision was published.
G-BA documents on this decision

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