[A25-135] Nivolumab (colorectal cancer with dMMR or MSI-H, first line, combination with ipilimumab) – Addendum to Project A25-80

Last updated 18.12.2025

Project no.:
A25-135

Commission:
Commission awarded on 28.10.2025 by the Federal Joint Committee (G-BA).

Report type:
Addendum

Status:
Commission completed

Department/Division:
Drug Assessment

Topic:
Cancer

Indication:

First-line treatment of adult patients with unresectable or metastatic colorectal cancer with mismatch repair deficiency or high microsatellite instability

Result of dossier assessment:

Unchanged after addendum: added benefit not proven

Note:

If the need for additional work on a project commissioned by the G-BA arises during consultations, then IQWiG presents a report in the form of an "addendum". The G-BA subsequently decides on the extent of the added benefit, thus completing the early benefit assessment.

DOI:

https://doi.org/10.60584/A25-135

Federal Joint Committee (G-BA)

2025-12-18 A G-BA decision was published.

G-BA documents on this decision

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