[A18-73] Abemaciclib in combination with fulvestrant (breast cancer) - Benefit assessment according to §35a Social Code Book V

Last updated 02.05.2019

Project no.:

Commission awarded on 29.10.2018 by the Federal Joint Committee (G-BA).

Report type:
Dossier assessment

Commission completed

Drug Assessment

Application field:


Women with HR-positive, HER2-negative locally advanced or metastatic breast cancer

Result of dossier assessment:

Initial or subsequent therapy in postmenopausal women: hint of lesser benefit in comparison with appropriate comparator therapy. Pre- or perimenopausal women: added benefit not proven due to lack of suitable study data.


After completion of the assessment by IQWiG the Federal Joint Committee (G-BA) conducts a commenting procedure. This may provide supplementary information and as a result lead to a modified benefit assessment. Further information and the decision on the early benefit assessment can be found on the relevant page of the G-BA website.

Federal Joint Committee (G-BA)

2019-05-02 A G-BA decision was published.

G-BA documents on this decision


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