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Medicine put to the test

As an independent scientific institute, IQWiG examines the benefits and harms of medical interventions for patients. We provide information about the advantages and disadvantages of examination and treatment methods in the form of scientific reports and easily understandable health information.

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Press Releases

Press Releases

Biomarker tests in breast cancer: decision on chemotherapy remains difficult

2016-12-05 Omitting chemotherapy can lead to more cases of distant metastasis and deaths. It cannot yet be judged whether this risk outweighs the chemotherapy-related burden.  read more Link to "Biomarker tests in breast cancer: decision on chemotherapy remains difficult"

Pembrolizumab in lung cancer: indication of considerable added benefit

2016-11-16 Advantages, e.g. in mortality, notably outweigh the disadvantages in some side effects in comparison with docetaxel. An added benefit over best supportive care is not proven.  read more Link to "Pembrolizumab in lung cancer: indication of considerable added benefit"

Trifluridine/tipiracil combination in colorectal cancer: added benefit only for some patients

2016-11-16 The drug combination offers survival advantages, but has also considerable side effects. An added benefit could only be derived in the non-mutant tumour type (KRAS wild type).  read more Link to "Trifluridine/tipiracil combination in colorectal cancer: added benefit only for some patients"

Corneal collagen cross-linking for keratoconus: now data provide hint of benefit

2016-11-15 Additional data from an Australian study now show an advantage over purely symptomatic treatment. However, overall the evidence is still insufficient.  read more Link to "Corneal collagen cross-linking for keratoconus: now data provide hint of benefit "

Sofosbuvir/velpatasvir in chronic hepatitis C: hint of added benefit in two of ten subindications

2016-10-17 Added benefit not proven for eight further subindications because the historical comparisons and considerations of individual study arms submitted were unsuitable for an assessment.  read more Link to "Sofosbuvir/velpatasvir in chronic hepatitis C: hint of added benefit in two of ten subindications"

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Easily understandable information for patients and the general community

Sinusitis

A stuffed-up nose, forehead and jaw pain, and a cough are typical symptoms of an inflammation of the sinuses, also called sinusitis. Sinusitis can be acute or chronic.  read more (Link to "Sinusitis" – opens in a new window)

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Glossary entries